The short answer is you can't get away with it. 1X LISA couldn't and it gets worse the bigger you go.
The medium length answer is that we need two side loaded to remove all play and get perfect rotational motion where the joints add nothing to the play. It will be hard enough to make sure the members can minimize the rest of the play. I am 100% sure that it would be a hot mess if I went with 1 bearing on LISA with all other thing left the same. We are talking about long arms here. My arms are 200mm long so if you had just 0.1degree play this would be 1/3 of mm play.
The medium length answer is that we need two side loaded to remove all play and get perfect rotational motion where the joints add nothing to the play. It will be hard enough to make sure the members can minimize the rest of the play. I am 100% sure that it would be a hot mess if I went with 1 bearing on LISA with all other thing left the same. We are talking about long arms here. My arms are 200mm long so if you had just 0.1degree play this would be 1/3 of mm play.